Epstein-Barr Virus (EBV) infects more than 90% of the adult population worldwide. EBV infection is associated with Burkitt lymphoma (BL) though alone is not sufficient to induce carcinogenesis implying the involvement of co-factors. BL is endemic in African regions faced with mycotoxins exposure. The Z. Herceg’s team demonstrated that the exposure to mycotoxins and oncogenic viruses has been shown to increase cancer risks partly through the deregulation of the immune response.